Transcript mining
نویسندگان
چکیده
منابع مشابه
Mining Mammalian Transcript Data for Functional Long Non-Coding RNAs
BACKGROUND The role of long non-coding RNAs (lncRNAs) in controlling gene expression has garnered increased interest in recent years. Sequencing projects, such as Fantom3 for mouse and H-InvDB for human, have generated abundant data on transcribed components of mammalian cells, the majority of which appear not to be protein-coding. However, much of the non-protein-coding transcriptome could mer...
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Mining massive amounts of transcript data for alternative splicing information is paramount to help understand how the maturation of RNA regulates gene expression. We developed an algorithm to cluster transcript data to annotated genes to detect unannotated splice variants. A higher number of alternatively spliced genes and isoforms were found compared to other alternative splicing databases. C...
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The frequent but unfortunate need to rework software development projects may often be caused by inappropriate decision making. The first step in addressing this issue is to explore decision making processes and to extract the tangible elements of decision making within meetings. This paper explores the hypothesis that text mining techniques can be used to extract the elements of decision makin...
متن کاملTranscript Mapping
The sequence of the 1173 nt 12S kinetoplast ribosomal RHA from TiPJ sfimarpa tarentolae was determined from the maxicircle DNA sequence, and the 5* and 3' ends localized by primer runoff and SI nuclease protection experiments. The gene was shown to be free of introns by SI nuclease analysis. A partial secondary structure model of the 12S RHA molecule is presented which is equivalent in certain ...
متن کاملNatural Antisense Transcript: A Concomitant Engagement with Protein-Coding Transcript
The vertebrate genome contains large spans of non-coding RNA, which for the most part were considered of little functional value to the organism. Recent studies have indicated that vertebrate genomes may have stored hidden secrets in this large span of non-coding RNA, which we refer to here as "Natural Antisense Transcripts (NATs)." NATs can be found in introns, exons, promoters, enhancers, int...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2000
ISSN: 1474-760X
DOI: 10.1186/gb-2000-1-1-reports230